Myelination of the Postnatal Mouse Cochlear Nerve at the Peripheral-Central Nervous System Transitional Zone
نویسندگان
چکیده
منابع مشابه
Myelination of the Postnatal Mouse Cochlear Nerve at the Peripheral-Central Nervous System Transitional Zone
In the nerve roots of vertebrates, the peripheral nervous system (PNS) and central nervous system (CNS) interface at the PNS-CNS transitional zone (PCTZ), which consists of cell boundaries with various myelin components. We have recently shown that the mouse cochlear nerve presents an exceptionally long segment of the CNS tissue extending into the PNS using light microscopy. However, it is uncl...
متن کاملFormation of the peripheral-central transitional zone in the postnatal mouse cochlear nerve.
OBJECTIVES Determine the formation of peripheral and central nervous system (CNS and PNS) transitional zone (PCTZ) along the postnatal mouse cochlear nerve. STUDY DESIGN Prospective, basic science. SETTING Research laboratory. SUBJECTS AND METHODS A novel cryosection model of cochlea-cochlear nerve-brainstem was used in this study. The sections were harvested from a total of 45 mice in 9 ...
متن کاملThe mechanical importance of myelination in the central nervous system.
Neurons in the central nervous system are surrounded and cross-linked by myelin, a fatty white substance that wraps around axons to create an electrically insulating layer. The electrical function of myelin is widely recognized; yet, its mechanical importance remains underestimated. Here we combined nanoindentation testing and histological staining to correlate brain stiffness to the degree of ...
متن کاملADENOSINE IN THE CENTRAL NERVOUS SYSTEM
Besides being a metabolite of nucleotides like ATP, adenosine is a mediator of neuronal function in the central nervous system. Its actions are mediated by at least three extracellular receptors. In this review different aspects of adenosine such as biosynthesis, release, inactivation and its receptors are discussed. It also covers pre- and postsynaptic effects as well as postreceptor mecha...
متن کاملChaperone Proteins in the Central Nervous System and Peripheral Nervous System after Nerve Injury
Injury to axons of the central nervous system (CNS) and the peripheral nervous system (PNS) is accompanied by the upregulation and downregulation of numerous molecules that are involved in mediating nerve repair, or in augmentation of the original damage. Promoting the functions of beneficial factors while reducing the properties of injurious agents determines whether regeneration and functiona...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Frontiers in Pediatrics
سال: 2013
ISSN: 2296-2360
DOI: 10.3389/fped.2013.00043